Academic Catalog

Genomics & Precision Medicine (GPM)

GPM 601  Research Methods and Ethics in Health and Genomics  3 Credits  
Grade Mode: Standard Letter, Audit/Non Audit  
  
This course aims to provide a comprehensive overview on research ethics, scientific thinking, and academic writing as well as guidelines for study design and good research practice. The course will also offer state-of-the-art knowledge relating to novel methods in genomics, precision medicine, and health analytics.
GPM 602  Clinical Applications in Genomics and Precision Medicine  3 Credits  
Grade Mode: Standard Letter, Audit/Non Audit  
  
This course covers fundamental concepts in the application of genomic and precision medicine in a clinical context. Included are modules on relevant technologies with emphasis on data interpretation for clinical outcome, drug design, as well as problem based learning components in clinical genomics and precision medicine
GPM 604  Advanced Genetics  3 Credits  
Grade Mode: Standard Letter, Audit/Non Audit  
  
The course covers important concepts and principles in genetics, such as inheritance, developmental processes, genetic variability, genetic mapping of diseases as well as genetic testing, DNA sequencing technologies, and treatment approaches to genetically inherited diseases.
GPM 607  Molecular Pathology  3 Credits  
Grade Mode: Standard Letter, Audit/Non Audit  
  
This course covers current concepts in molecular pathology and their application in translational research and diagnostics, with particular emphasis on the molecular pathology of cancer, cardiovascular, neurological and infectious disease.
GPM 695  Master's Thesis Hours  0-6 Credits  
Grade Mode: Pass/Non Pass  
  
Full time work in a laboratory to perform experiments related to the MS Thesis dissertation. Thesis research is an essential component of the graduate degree in Biological and Biomedical Sciences at HBKU. All students are required to engage in thesis research.
GPM 705  Introduction to Data Science  3 Credits  
Grade Mode: Standard Letter, Audit/Non Audit  
  
Genomics and precision medicine require handling, exploring and understanding large data sets. This course aims to introduce students to basic concepts from probability, statistical inference, linear regression and machine learning using R. No previous knowledge of programming is required, as the course will introduce basic programming concepts and through examples will enable students to ask the right questions, perform their own analyses and visualize the results effectively. The course will provide the students with hands-on programming experience.
GPM 720  Pharmacogenomics  3 Credits  
Grade Mode: Standard Letter, Audit/Non Audit  
  
This course covers fundamental concepts in the field of Pharmcogenomics and how it will help in the realization of personalized medicine. It will include the basic principles of drug discovery and design, pharmacology, pharmacogenetics and pharmacogenomics applied to several disease conditions.
GPM 721  Bioinformatics  3 Credits  
Grade Mode: Standard Letter, Audit/Non Audit  
  
The course will convey the fundamentals of bioinformatics methods for genomics data analysis to life science students. It aims to communicate the computational ideas behind key analysis methods in genomics and to provide practical training in using web-based tools and bioinformatics software packages in R. It will enable students to perform basic analysis steps for sequencing data. This course does not assume that the student has a background in mathematics and computer science, but rather introduces mathematical concepts and/or programming languages, as they are needed.
GPM 733  Epigenetics  3 Credits  
Grade Mode: Standard Letter, Audit/Non Audit  
  
GPM 733 is an elective epigenetic course. The course will provide an introduction to various epigenetic mechanisms and explain how they determine chromatin architecture and control gene expression. This is important to understand transcriptional regulation particularly during development, as well as during stem cell (re)programming. In addition, the course will cover how epigenetic alterations can cause aberrant silencing or activation of genes that can have an influence on health and disease. An acquaintance with the field of epigenetics is essential for a major in Genomics and Precision Medicine.
GPM 890  Dissertation Hours  0-9 Credits  
Grade Mode: Pass/Non Pass  
  
Full time work in a laboratory to perform experiments related to the PhD Thesis dissertation. Thesis research is an essential component of the graduate degree in Biological and Biomedical Sciences at HBKU. All students are required to engage in thesis research.